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The Impact of Body Weight Manipulation on Cognitive Performance and Present Psychological State in Combat Sports
Hrdlička, Jaroslav ; Pavelka, Radim (advisor) ; Harsa, Pavel (referee)
Title: The Impact of Body Weight Manipulation on Cognitive Performance and Present Psychological State in Combat Sports Objectives: The main objective of this diploma thesis is to investigate how Rapid Weight Loss (RWL) and subsequent Rapid Weight Gain (RWG) affect the cognitive performance and psychological state of combat sports athletes. A secondary objective is to examine the effects of these practices on body composition and, in the case of RWL, the effects on Urine Specific Gravity (USG). Methods: General information regarding pre-competition body weight manipulation experiences was obtained from 19 combat sports athletes who underwent weight reduction over a period of 7 days, followed by a 2-hour recovery period. Cognitive performance was assessed through various tests (simple reaction time test, choice reaction time test, and DSST) before and after RWL, and after RWG. Psychological state was assessed using standardized questionnaires (BRUMS and PANAS) before, during and after RWL, and after RWG. During RWL, USG and the methods used for RWL were also monitored. Results: The athletes reduced their body weight by 4.9% and subsequently regained 2.6% of body weight. RWL significantly impaired simple reaction time by 5.6% (16 ms). RWL also resulted in a statistically significant deterioration of...
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Clinical Applicability of Cognitive Testing in Huntington Disease
Mühlbäck, Alžbeta ; Klempíř, Jiří (advisor) ; Rusina, Robert (referee) ; Horáková, Hana (referee)
Introduction: Huntington disease (HD) is an autosomal dominant neurodegenerative disorder manifested by motor, behavioural and cognitive deficits with fatal consequences. Aims: This study aims to validate the psychometric properties of a standard cognitive battery used in HD and establish language-specific normative values. Methods: In the first study, cognitive performance was compared in 106 patients at different stages of HD and 100 healthy controls matched for age, sex, and education. The neuropsychological battery included the Symbol Digit Modalities Test, Stroop Word Reading Test, Stroop Colour Naming Test, Stroop Interference Test, Trail Making Test-A and B, Category and Letter Verbal Fluency. In addition, patients were comprehensively assessed for motor and functional status. In the second study, the cognitive performance of 3,267 healthy subjects was assessed. The work focused on the stratification of cognitive performance concerning age, gender, language and level of education. Another aim was to establish the language-specific normative values and implement a web-based normative calculator to assess the degree of cognitive deficit in different languages (English, German, Spanish, Italian, Polish, French, Dutch, Danish). Results: In the first study, analysis of variance showed that healthy...
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Cognitive screening tests and their potential to detect cognitive impairment in neurodegenerative diseases
Fendrych Mazancová, Adéla ; Bezdíček, Ondřej (advisor) ; Hladká, Adéla (referee) ; Hajdúk, Michal (referee)
Screening of global cognitive performance is of great importance in the detection of early cognitive impairment in neurodegenerative diseases. In contrast to complex neuropsychological assessment, cognitive screening tests offer some advantages as saving time or finance and administration of screening tests makes lower demands on clinicians. Validation of cognitive screening tests for specific diagnostic groups of patients is necessary as well as Czech normative studies that enable an objective evaluation of the cognitive performance of Czech patients. In the theoretical part, we presented the syndrome of mild cognitive impairment as a pre-dementia state in neurodegenerative diseases. We focused on the assessment of mild cognitive impairment and using five different cognitive screening tests (Mini-Mental State Examination, Montreal Cognitive Assessment, Dementia Rating Scale 2. edition, Frontal Assessment Battery, Clock Drawing Test) in the detection of cognitive impairment. Then we focused on Parkinson's disease (PD), especially on the evolution of different stages of cognitive deficit in PD and their detection by cognitive assessments. The empirical research included studies analyzing the potential of the five cognitive screening tests to detect mild cognitive impairment. We provided results...
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